Sodium Bicarbonate

Sodium Bicarbonate

Mechanism of Action: Sodium bicarbonate is a salt that breaks down in fluids, including blood and urine, to form sodium and bicarbonate. This breakdown buffers the blood and makes it less acidic.

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Indications: Sodium bicarbonate is an antacid used to relieve heartburn and acid indigestion

Precautions: Pregnancy and breast-feeding: Sodium bicarbonate is possibly unsafe when taken by mouth or used intravenously during pregnancy. There is some concern that it might increase the risk of water retention or pH imbalances in the tissues.

Use caution in patients with cirrhosis, heart failure, renal impairment, peptic ulcer disease, or edema

People with high calcium levels in the blood can have trouble excreting bicarbonate. Therefore, using sodium bicarbonate might increase the risk of complications such as milk-alkali syndrome.

Sodium bicarbonate might increase sodium levels in the blood.

Sodium bicarbonate might increase blood pressure.

Sodium bicarbonate might lower potassium blood levels.

Sodium bicarbonate decreases how much iron the body absorbs. People with iron deficiency should take sodium bicarbonate and iron supplements separately.

Adverse Reactions:


· slow breathing

· swelling of feet or lower legs

· bloody, black, or tarry stools

· blood in your urine

· severe headache

· nausea

· High blood sodium levels

· Low blood calcium levels

· Low blood potassium levels

· Aggravated congestive heart failure

· vomit that resembles coffee grounds

· loss of appetite

· irritability

· weakness

· frequent urge to urinate

· increased thirst

· stomach cramps

· gas



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Sodium bicarbonate DOSAGE guide + Max Dose, Adjustments. (n.d.). Retrieved September 12, 2021, from

Sodium bicarbonate dosing, indications, interactions, adverse effects, and more. (2021, January 8). Retrieved September 12, 2021, from

U.S. National Library of Medicine. (n.d.). Sodium Bicarbonate: MEDLINEPLUS drug information. MedlinePlus. Retrieved September 12, 2021, from

WebMD. (n.d.). Sodium bicarbonate: Overview, uses, side effects, precautions, interactions, dosing and reviews. WebMD. Retrieved September 12, 2021, from


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