P/O Ratios

The P/O ratio of a compound refers to the number of ATP produced when two electrons from the said compound reduce oxygen to produce 1 molecule of water.

Assuming 4 H+ are needed per ATP synthesized, what is the P/O ratio of the following compounds:

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  1. NADH
  2. FADH2
  3. Ubiquinol
  4. Tetramethyl-p-phenylenediamine – this compound donates 2 electrons directly to complex IV of the mitochondrial ETC.


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