Off-Label Drug Use in Pediatrics

Assignment: Off-Label Drug Use in Pediatrics

 

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The unapproved use of approved drugs, also called off-label use, with children is quite common. This is because pediatric dosage guidelines are typically unavailable, since very few drugs have been specifically researched and tested with children.

When treating children, prescribers often adjust dosages approved for adults to accommodate a child’s weight. However, children are not just “smaller” adults. Adults and children process and respond to drugs differently in their absorption, distribution, metabolism, and excretion.

Children even respond differently during stages from infancy to adolescence. This poses potential safety concerns when prescribing drugs to pediatric patients. As an advanced practice nurse, you have to be aware of safety implications of the off-label use of drugs with this patient group.

 

Assignment Week 11 – instructions

 

Write a narrative in APA7 format that addresses the following:

 

  • Explain the circumstances under which children should be prescribed drugs for off-label use. Be specific and provide examples.

 

  • Describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.

 

  • At least 5 references

 

Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. All papers submitted must use APA 7

 

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