Anion Gaps

Based on your readings and your research define and describe Anion Gaps and their clinical significance.

Anion gap refers to the difference in charge between positively and negatively charged ions (Heireman et al., 2018). Salts dissociate into ions when they dissolve into electrolyte solutions like serum and extracellular fluid. Depending on the solutes, the solution can contain more cations than anions. Examples of positively charged ions include hydrogen ions, potassium, and sodium ions. Bicarbonate ions are the most common anions in serum. If every cation is matched to an anion, any remnant ions constitute the anion gap. Normal anion gap ranges between 10 and 13 mEq/L and deviations from this range indicate electrolytic derangements (Heireman et al., 2018). Ms. Brown’s anion gap, which sums up to 25 mEq/L suggests an acidosis. A low anion gap below 10 mEq/L would have indicated a deficiency of hydrogen ions. Such insights provide additional information for the diagnosis and correction of acid-base irregularities

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