Amino Acids

Amino Acids

1. Determine if the following statements are TRUE or FALSE. If the statement is FALSE
provide and explanation as to why.
a. Serine is classified as a polar amino acid.
b. The amino acid V is classified as a neutral polar amino acid.
c. The amino acid Y can form hydrogen bonds.
d. In a protein, disulfide bonds are formed between the side chains of Met
amino acids.
e. All of the amino acids are chiral.
f. The amino acids W, F, and Y are classified as aromatic amino acids.
g. In a protein, the amino acids D and K (that are close together) would likely
form Van Der Waals interactions.
h. In a protein, the amino acids K and N (that are close together) would likely
form hydrogen bonds.
i. In a protein, the amino acids V, I, L, and would be found on the surface
exposed to the aqueous surroundings.
j. At pH 10 the side chain of C would most likely be in its fully protonated
uncharged form.
2. The isoelectric point is the pH at which a chemical species has no net charge.
Based on the pKa values of the α-amine and α-carboxylic acid groups in a alanine
amino acid. Estimate its isoelectric point.
3. Based on the same rationale you used in Q2 estimate the isoelectric points of
Glutamic acid, and Arginine.
4. Describe how you would calculate the isoelectric points of Alanine, Aspartic acid,
and Lysine.

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